PGE2 protects against heart failure through inhibiting TGF-I31 synthesis in cardiomyocytes and crosstalk between TGF-I31 and GRK2

Fu, J; Li, L; Chen, L; Su, CP; Feng, XL; Huang, K; Zhang, LX; Yang, XY; Fu, Q

Yang, XY; Fu, Q (通讯作者)，Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Basic Med, Dept Pharmacol, Wuhan 430000, Peoples R China.;Zhang, LX (通讯作者)，Wenchang Peoples Hosp, Div Cardiol, Wenchang 571300, Peoples R China.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2022; 172 (): 63

Abstract

Inflammation plays a central role in the development of heart failure. Prostaglandin E2 (PGE2) is a key mediator of the inflammatory process in the ca......

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