Cochlear Neurotrophin-3 overexpression at mid-life prevents age-related inner hair cell synaptopathy and slows age-related hearing loss

Cassinotti, LR; Ji, LC; Borges, BC; Cass, ND; Desai, AS; Kohrman, DC; Liberman, MC; Corfas, G

Corfas, G (通讯作者),Univ Michigan, Dept Otolaryngol Head & Neck Surg, Med Sci 1 Bldg,Rm 5428,1150 West Med Ctr Dr, Ann Arbor, MI 48109 USA.;Corfas, G (通讯作者),Univ Michigan, Kresge Hearing Res Inst, Med Sci 1 Bldg,Rm 5428,1150 West Med Ctr Dr, Ann Arbor, MI 48109 USA.

AGING CELL, 2022; 21 (10):

Abstract

Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly. This progressive pathology often has psychological and medical c......

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