Oncogene addiction to GNAS in GNAS(R201) mutant tumors

More, A; Ito, I; Haridas, V; Chowdhury, S; Gu, Y; Dickson, P; Fowlkes, N; Shen, JP

Shen, JP (通讯作者),MD Anderson Canc Ctr, Dept GI Med Oncol, Houston, TX 77030 USA.

ONCOGENE, 2022; 41 (35): 4159

Abstract

The GNAS(R201) gain-of-function mutation is the single most frequent cancer-causing mutation across all heterotrimeric G proteins, driving oncogenesis......

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