C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid

Hornum, L; Hansen, AJ; Tornehave, D; Fjording, MS; Colmenero, P; Watjen, IF; Nielsen, NHS; Bliddal, H; Bartels, EM

Bartels, EM (reprint author), Copenhagen Univ Hosp, Parker Inst, Frederiksberg, Denmark.

PLOS ONE, 2017; 12 (12):

Abstract

Complement activation correlates to rheumatoid arthritis disease activity, and increased amounts of the complement split product C5a is observed in sy......

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