Abemaciclib Inhibits Renal Tubular Secretion Without Changing Glomerular Filtration Rate

Chappell, JC; Turner, PK; Pak, YA; Bacon, J; Chiang, AY; Royalty, J; Hall, SD; Kulanthaivel, P; Bonventre, JV

Turner, PK (reprint author), Eli Lilly & Co, Indianapolis, IN 46285 USA.

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2019; 105 (5): 1187

Abstract

Abemaciclib, an inhibitor of cyclin dependent kinases 4 and 6, is indicated for metastatic breast cancer treatment. Reversible increases in serum crea......

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