Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients

Yang, K; Kong, RA; Spiegel, R; Baird, JD; O'Keefe, K; Howell, BA; Watkins, PB

Yang, K (通讯作者),Simulat Plus Inc, Quantitat Syst Pharmacol Solut, Res Triangle Pk, NC 27709 USA.

CLINICAL PHARMACOLOGY & THERAPEUTICS, 2023; ():

Abstract

Clinical investigation of emvododstat for the treatment of solid tumors was halted after two patients who were heavily treated with other anticancer t......

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