TP-0903 is active in models of drug-resistant acute myeloid leukemia

Jeon, JY; Buelow, DR; Garrison, DA; Niu, MS; Eisenmann, ED; Huang, KM; Thomas, MEZ; Weber, RH; Whatcott, CJ; Warner, SL; Orwick, SJ; Carmichael, B; Stahl, E; Brinton, LT; Lapalombella, R; Blachly, JS; Hertlein, E; Byrd, JC; Bhatnagar, B; Baker, SD

Baker, SD (corresponding author), 410 Biomed Res Tower,460 W 12th Ave, Columbus, OH 43210 USA.

JCI INSIGHT, 2020; 5 (23):

Abstract

Effective treatment for AML is challenging due to the presence of clonal heterogeneity and the evolution of polyclonal drug resistance. Here, we repor......

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