Monensin-Induced Increase in Intracellular Na+ Induces Changes in Na+ and Ca2+ Currents and Regulates Na+-K+ and Na+-Ca2+ Transport in Cardiomyocytes

Tsuchida, K; Hirose, H; Ozawa, S; Ishida, H; Iwatani, T; Matsumoto, U

Tsuchida, K (corresponding author), Doshisha Womens Coll, Fac Pharmaceut Sci, Dept Rat Med Sci, 97-1 Minamihokodate, Kode, Kyotababe 6100395, Japan.

PHARMACOLOGY, 2021; 106 (1-2): 91

Abstract

Background/Aims: Monensin, an Na ionophore, increases intracellular Na ([Na]i). Alteration of [Na]i influences ion transport through the sarcolemmal m......

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