Longitudinal serum metabolomics evaluation of trastuzumab and everolimus combination as pre-operative treatment for HER-2 positive breast cancer patients

Jobard, E; Tredan, O; Bachelot, T; Vigneron, AM; Ait-Oukhatar, CM; Arnedos, M; Rios, M; Bonneterre, J; Dieras, V; Jimenez, M; Merlin, JL; Campone, M; Elena-Herrmann, B

Elena-Herrmann, B (reprint author), Univ Lyon 1, CNRS, Inst Sci Analyt, UMR 5280,ENS Lyon, Villeurbanne, France.; Campone, M (reprint author), Ctr Rene Gauducheau, Inst Cancerol Ouest, St Herblain, France.

ONCOTARGET, 2017; 8 (48): 83570

Abstract

The mammalian target of rapamycin complex 1 (mTORC1) is an attractive target for HER-2 positive breast cancer therapy because of its key role in prote......

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