Detection of the hepatitis B virus (HBV) covalently-closed-circular DNA (cccDNA) in mice transduced with a recombinant AAV-HBV vector

Lucifora, J; Salvetti, A; Marniquet, X; Mailly, L; Testoni, B; Fusil, F; Inchauspe, A; Michelet, M; Michel, ML; Levrero, M; Cortez, P; Baumert, TF; Cosset, FL; Challier, C; Zoulim, F; Durantel, D

Zoulim, F; Durantel, D (reprint author), CNRS 5286, CRCL, UMR INSERM U1052, 151 Cours Albert Thomas, F-69424 Lyon 03, France.

ANTIVIRAL RESEARCH, 2017; 145 ( ): 14

Abstract

Hepatitis B Virus (HBV) persists in infected hepatocytes as an episomal covalently-closed-circular DNA mini-chromosome, called cccDNA. As the main nuc......

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