Lack of APOL1 in proximal tubules of normal human kidneys and proteinuric APOL1 transgenic mouse kidneys

Blessing, NA; Wu, ZZ; Madhavan, SM; Choy, JW; Chen, M; Shin, MK; Hoek, M; Sedor, JR; O'Toole, JF; Bruggeman, LA

Bruggeman, LA (corresponding author), Case Western Reserve Univ, Dept Inflammat & Immun, Cleveland Clin, Sch Med, Cleveland, OH 44106 USA.; Bruggeman, LA (corresponding author), Case Western Reserve Univ, Dept Nephrol, Cleveland Clin, Sch Med, Cleveland, OH 44106 USA.

PLOS ONE, 2021; 16 (6):

Abstract

The mechanism of pathogenesis associated with APOL1 polymorphisms and risk for non-diabetic chronic kidney disease (CKD) is not fully understood. Prio......

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