LFZ-4-46, a tetrahydroisoquinoline derivative, induces apoptosis and cell cycle arrest via induction of DNA damage and activation of MAPKs pathway in cancer cells

Xu, LL; Huang, GZ; Zhu, ZH; Tian, SS; Wei, YY; Hong, HW; Lu, XW; Li, Y; Liu, FZ; Zhao, HJ

Zhao, HJ (corresponding author), Zhejiang Chinese Med Univ, Hangzhou 310053, Peoples R China.

ANTI-CANCER DRUGS, 2021; 32 (8): 842

Abstract

LFZ-4-46, that is [2-hydroxy-1-phenyl-1,5,6,10b-tetrahydropyrazolo(5,1-a) isoquinolin-3(2H)-yl](phenyl) methanone, a tetrahydroisoquinoline derivative......

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