Engineering nanoparticles to locally activate T cells in the tumor microenvironment

Wang, DG; Wang, TT; Yu, HJ; Feng, B; Zhou, L; Zhou, FY; Hou, B; Zhang, HW; Luo, M; Li, YP

Yu, HJ; Li, YP (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China.; Yu, HJ; Li, YP (reprint author), Chinese Acad Sci, Shanghai Inst Mat Med, Ctr Pharmaceut, Shanghai 201203, Peoples R China

SCIENCE IMMUNOLOGY, 2019; 4 (37):

Abstract

Immunological tolerance of tumors is characterized by insufficient infiltration of cytotoxic T lymphocytes (CTLs) and immunosuppressive microenvironme......

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