Clinical-Grade Expanded Regulatory T Cells Are Enriched with Highly Suppressive Cells Producing IL-10, Granzyme B, and IL-35

Ulbar, F; Villanova, I; Giancola, R; Baldoni, S; Guardalupi, F; Fabi, B; Olioso, P; Capone, A; Sola, R; Ciardelli, S; Del Papa, B; Brattelli, A; Ricciardi, I; Taricani, S; Sabbatinelli, G; Iuliani, O; Passeri, C; Sportoletti, P; Santarone, S; Pierini, A; Calabrese, G; Falzetti, F; Bonfini, T; Accorsi, P; Ruggeri, L; Martelli, MF; Velardi, A; Di Ianni, M

Di Ianni, M (corresponding author), Univ G dAnnunzio, Dept Med & Aging Sci, Via Fonte Romana 8, I-65127 Pescara, Italy.; Di Ianni, M (corresponding author), Osped Pescara, Dept Oncol Hematol, Via Fonte Romana 8, I-65127 Pescara, Italy.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2020; 26 (12): 2204

Abstract

In the setting of T cell-depleted, full-haplotype mismatched transplantation, adoptive immunotherapy with regulatory T cells (Tregs) and conventional ......

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