Defective dimerization of FoF1-ATP synthase secondary to glycation favors mitochondrial energy deficiency in cardiomyocytes during aging

Bou-Teen, D; Fernandez-Sanz, C; Miro-Casas, E; Nichtova, Z; Bonzon-Kulichenko, E; Casos, K; Inserte, J; Rodriguez-Sinovas, A; Benito, B; Sheu, SS; Vazquez, J; Ferreira-Gonzalez, I; Ruiz-Meana, M

Ferreira-Gonzalez, I; Ruiz-Meana, M (通讯作者),Vall dHebron Hosp Univ, Vall dHebron Inst Recerca VHIR, Cardiovasc Dis Res Grp, Vall dHebron Barcelona Hosp Campus, Barcelona 08035, Spain.

AGING CELL, 2022; 21 (3):

Abstract

Aged cardiomyocytes develop a mismatch between energy demand and supply, the severity of which determines the onset of heart failure, and become prone......

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