Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders

Du, JJM; Simmons, S; Brunklaus, A; Adiconis, X; Hession, CC; Fu, ZY; Li, YQ; Shema, R; Moller, RS; Barak, B; Feng, GP; Meisler, M; Sanders, S; Lerche, H; Campbell, AJ; McCarroll, S; Levin, JZ; Lal, D

Lal, D (corresponding author), Cleveland Clin, Genom Med Inst, Neurol Inst, Cleveland, OH 44106 USA.; Brunklaus, A (corresponding author), Royal Hosp Children, Paediat Neurosci Res Grp, Off Block,Ground Floor,Zone 2,1345 Govan Rd, Glasgow G51 4TF, Lanark, Scotland.

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2020; 24 (): 129

Abstract

The four voltage-gated sodium channels SCN1/2/3/8A have been associated with heterogeneous types of developmental disorders, each presenting with dise......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索