The pharmacologic and toxicologic characterization of the potent and selective KRAS G12D inhibitors ERAS-4693 and ERAS-5024

Brooun, A; Zhang, JC; Li, CY; Lam, R; Cheng, HM; Shoemaker, R; Daly, J; Olaharski, A

Shoemaker, R (通讯作者)，Erasca Therapeut, San Diego, CA 92121 USA.

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2023; 474 ():

Abstract

Two potent and selective KRASG12D inhibitors, ERAS-4693 and ERAS-5024, were generated as possible clinical candidates to treat patients harboring G12D......

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