Preparation of a Major Metabolite of Iguratimod and Simultaneous Assay of Iguratimod and Its Metabolite by HPLC in Rat Plasma

Han, JP; Zhu, ZH; Wu, YZ; Qian, W; Li, ZY; Nishikawa, M; Sakaki, T; Yang, CQ

Yang, CQ (reprint author), China Pharmaceut Univ, Sch Basic Med & Clin Pharm, Dept Clin Pharm, 639 Longmian Ave, Jiangning Dist, Jiangsu, Peoples R China.; Yang, CQ (reprint author), Nanjing BRT Biomed Co Ltd, Jiangning Dist, Jiangsu, Peoples R China.

IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2019; 18 (2): 631

Abstract

Iguratimod is a new synthetic disease-modifying antirheumatic drug intended to treat patients with rheumatoid arthritis. A new method using recombinan......

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