CTLA-4 expressed by FOXP3(+) regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis

Klocke, K; Holmdahl, R; Wing, K

Wing, K (reprint author), Karolinska Inst, Div Med Inflammat Res, Dept Med Biochem & Biophys, S-17177 Stockholm, Sweden.

IMMUNOLOGY, 2017; 152 (1): 125

Abstract

Cytotoxic T-lymphocyte antigen 4 (CTLA-4) -mediated regulation of already tolerized autoreactive T cells is critical for understanding autoimmune resp......

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