Accelerated epigenetic aging in newborns with Down syndrome

Xu, KR; Li, SB; Muskens, IS; Elliott, N; Myint, SS; Pandey, P; Hansen, HM; Morimoto, LM; Kang, AY; Ma, XM; Metayer, C; Mueller, BA; Roberts, I; Walsh, KM; Horvath, S; Wiemels, JL; Smith, AJ

Smith, AJ (通讯作者),USC Norris Comprehens Canc Ctr, Ctr Genet Epidemiol, 1450 Biggy St,NRT 1509H, Los Angeles, CA 90033 USA.

AGING CELL, 2022; 21 (7):

Abstract

Accelerated aging is a hallmark of Down syndrome (DS), with adults experiencing early-onset Alzheimer's disease and premature aging of the skin, hair,......

Full Text Link