Optimization of CFTR gating through the evolution of its extracellular loops

Simon, MA; Csanády, L

Simon, MA (通讯作者),Semmelweis Univ, Dept Biochem, Budapest, Hungary.;Simon, MA (通讯作者),HCEMM SE Mol Channelopathies Res Grp, Budapest, Hungary.;Simon, MA (通讯作者),ELKH SE Ion Channel Res Grp, Budapest, Hungary.

JOURNAL OF GENERAL PHYSIOLOGY, 2023; 155 (4):

Abstract

CFTR chloride channel mutations cause the lethal and incurable disease cystic fibrosis (CF). CFTR is activated by phosphorylation, and phosphorylated ......

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