Cardiolipin interacts with beta-2-glycoprotein I and forms an open conformation-Mechanisms analyzed using hydrogen/deuterium exchange

Tang, KT; Wu, TY; Chen, HH; Lin, CC; Hsu, YHH

Hsu, YHH (corresponding author), Tunghai Univ, Dept Chem, 1727,Sec 4,Taiwan Blvd, Taichung 40704, Taiwan.

PROTEIN SCIENCE, ; ():

Abstract

Beta-2-glycoprotein I (beta(2)GPI) is the major antigen for the antiphospholipid antibodies in the antiphospholipid syndrome. The exposed epitope in d......

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