Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging

Yokoyama, JS; Marx, G; Brown, JA; Bonham, LW; Wang, D; Coppola, G; Seeley, WW; Rosen, HJ; Miller, BL; Kramer, JH; Dubal, DB

Yokoyama, JS; Dubal, DB (reprint author), Univ Calif San Francisco, Dept Neurol, 675 Nelson Rising Lane, San Francisco, CA 94158 USA.

BRAIN IMAGING AND BEHAVIOR, 2017; 11 (2): 391

Abstract

Cognitive decline is a major biomedical challenge as the global population ages. Elevated levels of the longevity factor klotho suppress aging, enhanc......

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