Nuclear genome-wide associations with mitochondrial heteroplasmy

Nandakumar, P; Tian, C; O'Connell, J; Hinds, D; Paterson, AD; Sondheimer, N

Hinds, D (corresponding author), 23AndMe Inc, 223 N Mathilda Ave, Sunnyvale, CA 94086 USA.; Sondheimer, N (corresponding author), Hosp Sick Children, Program Genet & Genome Biol, Toronto, ON, Canada.

SCIENCE ADVANCES, 2021; 7 (12):

Abstract

The role of the nuclear genome in maintaining the stability of the mitochondrial genome (mtDNA) is incompletely known. mtDNA sequence variants can exi......

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