mTOR drives cerebrovascular, synaptic, and cognitive dysfunction in normative aging

Van Skike, CE; Lin, AL; Burbank, RR; Halloran, JJ; Hernandez, SF; Cuvillier, J; Soto, VY; Hussong, SA; Jahrling, JB; Javors, MA; Hart, MJ; Fischer, KE; Austad, SN; Galvan, V

Galvan, V (reprint author), Univ Texas Hlth San Antonio, Barshop Inst Longev & Aging Studies, Dept Cellular & Integrat Physiol, 15355 Lambda Dr STCBM 3-341, San Antonio, TX 78245 USA.

AGING CELL, 2020; 19 (1):

Abstract

Cerebrovascular dysfunction and cognitive decline are highly prevalent in aging, but the mechanisms underlying these impairments are unclear. Cerebral......

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