Cryo-EM structures of human p97 double hexamer capture potentiated ATPase-competent state

Gao, HS; Li, FX; Ji, ZJ; Shi, ZB; Li, Y; Yu, HT

Gao, HS; Yu, HT (通讯作者)，Westlake Univ, Sch Life Sci, Hangzhou, Zhejiang, Peoples R China.;Gao, HS; Yu, HT (通讯作者)，Westlake Lab Life Sci & Biomed, Hangzhou, Zhejiang, Peoples R China.;Gao, HS; Yu, HT (通讯作者)，Univ Texas Southwestern Med Ctr Dallas, Dept Pharmacol, Dallas, TX 75390 USA.

CELL DISCOVERY, 2022; 8 (1):

Abstract

The conserved ATPase p97 (Cdc48 in yeast) and adaptors mediate diverse cellular processes through unfolding polyubiquitinated proteins and extracting ......

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