Aromatase-induced endogenous estrogen promotes tumour metastasis through estrogen receptor-alpha/matrix metalloproteinase 12 axis activation in castration-resistant prostate cancer-MedSci.cn

Aromatase-induced endogenous estrogen promotes tumour metastasis through estrogen receptor-alpha/matrix metalloproteinase 12 axis activation in castration-resistant prostate cancer

Liang, ZX; Cao, JS; Tian, L; Shen, YM; Yang, X; Lin, QM; Zhang, R; Liu, HT; Du, XL; Shi, JD; Zhang, J

Shi, JD; Zhang, J (reprint author), Nankai Univ, Dept Biochem & Mol Biol, Coll Life Sci, Bioact Mat Key Lab,Minist Educ, Tianjin 300071, Peoples R China.

CANCER LETTERS, 2019; 467 (): 72

Abstract

Castration-resistant prostate cancer (CRPC) following androgen deprivation therapy remains a major obstacle advanced prostate cancer management. Aroma......

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