Design of novel Xenopus GLP-1-based dual glucagon-like peptide 1 (GLP-1)/glucagon receptor agonists

Jiang, N; Jing, L; Li, Q; Su, SB; Yang, QM; Zhou, F; Chen, XY; Han, J; Tang, CL; Tang, WZ

Tang, CL (corresponding author), Guangxi Med Univ, Dept Pharm, Affiliated Tumor Hosp, Nanning, Peoples R China.; Tang, WZ (corresponding author), Guangxi Med Univ, Dept Gastrointestinal Surg, Affiliated Tumor Hosp, Nanning, Peoples R China.; Han, J (corresponding author), Jiangsu Normal Univ, Sch Chem & Mat Sci, Xuzhou 221116, Jiangsu, Peoples R China.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021; 212 ():

Abstract

Dual activation of the glucagon receptor (GCGR) and glucagon-like peptide 1 receptor (GLP-1R) has the potential to lead to an effective therapy for th......

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