Porcine cGAS-STING signaling induced autophagy inhibits STING downstream IFN and apoptosis

Xia, NW; Zheng, WL; Jiang, S; Cao, Q; Luo, J; Zhang, JJ; Xu, YL; Sun, SH; Zhang, KL; Chen, NH; Meurens, F; Zhu, JZ

Zhu, JZ (通讯作者)，Yangzhou Univ, Comparat Med Res Inst, Yangzhou, Peoples R China.;Zhu, JZ (通讯作者)，Yangzhou Univ, Coll Vet Med, Yangzhou, Peoples R China.;Zhu, JZ (通讯作者)，Joint Int Res Lab Agr & Agriprod Safety, Yangzhou, Peoples R China.;Zhu, JZ (通讯作者)，Yangzhou Univ, Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou, Peoples R China.

FRONTIERS IN IMMUNOLOGY, 2022; 13 ():

Abstract

The innate immune DNA sensing cGAS-STING signaling pathway has been widely recognized for inducing interferons (IFNs) and subsequent antiviral state. ......

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