Physiological clearance of A beta by spleen and splenectomy aggravates Alzheimer-type pathogenesis

Yu, ZY; Chen, DW; Tan, CR; Zeng, GH; He, CY; Wang, J; Bu, XL; Wang, YJ

Wang, J; Bu, XL; Wang, YJ (通讯作者),Third Mil Med Univ, Daping Hosp, Dept Neurol, Chongqing, Peoples R China.;Wang, J; Bu, XL; Wang, YJ (通讯作者),Third Mil Med Univ, Daping Hosp, Ctr Clin Neurosci, Chongqing, Peoples R China.

AGING CELL, 2022; 21 (1):

Abstract

Background A previous study demonstrated that nearly 40%-60% of brain A beta flows out into the peripheral system for clearance. However, where and ho......

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