Oxidized Phosphatidylcholines Trigger TRPA1 and Ryanodine Receptor-dependent Airway Smooth Muscle Contraction

Vaghasiya, J; Dalvand, A; Sikarwar, A; Mangat, D; Ragheb, M; Kowatsch, K; Pandey, D; Hosseini, SM; Hackett, TL; Karimi-Abdolrezaee, S; Ravandi, A; Pascoe, CD; Halayko, AJ

Halayko, AJ (通讯作者)，Univ Manitoba, Childrens Hosp, Res Inst Manitoba, Sixth Floor,715 McDermott Ave, Winnipeg, MB R3E 3P4, Canada.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2023; 69 (6): 649

Abstract

Asthma pathobiology includes oxidative stress that modifies cell membranes and extracellular phospholipids. Oxidized phosphatidylcholines (OxPCs) in l......

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