Cinobufagin inhibits proliferation of acute myeloid leukaemia cells by repressing c-Myc pathway-associated genes

Hirasaki, Y; Okabe, A; Fukuyo, M; Rahmutulla, B; Mano, Y; Seki, M; Hoshii, T; Namiki, T; Kaneda, A

Kaneda, A (通讯作者)，Chiba Univ, Grad Sch Med, Dept Mol Oncol, Chuo Ku, 1-8-1 Inohana, Chiba 2608670, Japan.

CHEMICO-BIOLOGICAL INTERACTIONS, 2022; 360 ():

Abstract

Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad, Bufo gargarizans. Bufanolides inhibit Na+/K+ ATPase and have similar eff......

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