Efferocytosis fuels malignant pleural effusion through TIMP1

Zhao, LL; Giannou, AD; Xu, Y; Shiri, AM; Liebold, I; Steglich, B; Bedke, T; Zhang, T; Lucke, J; Scognamiglio, P; Kempski, J; Woestemeier, A; Chen, J; Agalioti, T; Zazara, DE; Lindner, D; Janning, M; Hennigs, JK; Jagirdar, RM; Kotsiou, OS; Zarogiannis, SG; Kobayashi, Y; Izbicki, JR; Ghosh, S; Rothlin, CV; Bosurgi, L; Huber, S; Gagliani, N

Gagliani, N (corresponding author), Univ Med Ctr Hamburg Eppendorf, Dept Gen Visceral & Thorac Surg, D-20246 Hamburg, Germany.; Bosurgi, L; Huber, S (corresponding author), Univ Med Ctr Hamburg Eppendorf, Dept Med 1, Sect Mol Immunol & Gastroenterol, D-20246 Hamburg, Germany.; Bosurgi, L (corresponding author), Bernard Nocht Inst Trop Med, Protozoa Immunol, D-20359 Hamburg, Germany.; Gagliani, N (corresponding author), Karolinska Inst, Dept Med, Immunol & Allergy Unit, S-17176 Stockholm, Sweden.

SCIENCE ADVANCES, 2021; 7 (33):

Abstract

Malignant pleural effusion (MPE) results from the capacity of several human cancers to metastasize to the pleural cavity. No effective treatments are ......

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