Homologous recombination deficiency (HRD) signature-3 in ovarian and uterine carcinosarcomas correlates with preclinical sensitivity to Olaparib, a poly (adenosine diphosphate [ADP]- ribose) polymerase (PARP) inhibitor

Tymon-Rosario, JR; Manara, P; Manavella, DD; Bellone, S; Hartwich, TMP; Harold, J; Yang-Hartwich, Y; Zipponi, M; Choi, J; Jeong, K; Mutlu, L; Yang, KV; Altwerger, G; Menderes, G; Ratner, E; Huang, GS; Clark, M; Andikyan, V; Azodi, M; Schwartz, PE; Alexandrov, LB; Santin, AD

Santin, AD (通讯作者)，33 Cedar St,LSOG 305,POB 208063, New Haven, CT 06520 USA.

GYNECOLOGIC ONCOLOGY, 2022; 166 (1): 117

Abstract

Objectives. Carcinosarcoma (CS) of the ovary and uterus are highly aggressive malignancies associated with poor survival. Poly(ADP-ribose)-polymerase ......

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