A challenge finding P2X1 and P2X4 ligands

Beswick, P; Wahab, B; Honey, MA; Paradowski, M; Jiang, K; Lochner, M; Murrell-Lagnado, RD; Thompson, AJ

Thompson, AJ (reprint author), Univ Cambridge, Dept Pharmacol, Cambridge, England.

NEUROPHARMACOLOGY, 2019; 157 ():

Abstract

Identifying novel small-molecule P2X1 and P2X4 ligands with sub-type specificity and high-affinity remains a pharmacological challenge. Here we use co......

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