Direct-acting antiviral therapy enhances total CD4+and CD8+T-cells responses, but does not alter T-cells activation among HCV mono-infected, and HCV/HIV-1 co-infected patients-MedSci.cn

Direct-acting antiviral therapy enhances total CD4+and CD8+T-cells responses, but does not alter T-cells activation among HCV mono-infected, and HCV/HIV-1 co-infected patients

Fard, SN; Schietromaa, I; Scheri, GC; Giustini, N; Serafinoa, S; Cavallari, EN; Pinacchio, C; De Girolamo, G; Ceccarelli, G; Scagnolari, C; Vullo, V; d'Ettorre, G

Fard, SN (reprint author), Sapienza Univ Rome, Dept Publ Hlth & Infect Dis, Policlin Umberto 1, Viale Policlin 155, I-00161 Rome, Italy.

Abstract

Aim: Chronic immune activation and poor T-cell immune response are strongly associated with disease progression and pathogenesis of both hepatitis C v......

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Direct-acting antiviral therapy enhances total CD4+and CD8+T-cells responses, but does not alter T-cells activation among HCV mono-infected, and HCV/HIV-1 co-infected patients

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