Inhibition of COX-2/mPGES-1 and 5-LOX in macrophages by leonurine ameliorates monosodium urate crystal-induced inflammation

Liu, YZ; Duan, CF; Chen, HL; Wang, CL; Liu, XX; Qiu, M; Tang, HL; Zhang, F; Zhou, XY; Yang, J

Yang, J (reprint author), Wuhan Univ, Sch Basic Med Sci, Dept Pharmacol, Wuhan 430071, Hubei, Peoples R China.

TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018; 351 (): 1

Abstract

Cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX) and microsomal prostaglandin E synthase-1 (mPGES-1)derived eicosanoids play an essential role in huma......

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