Is AAV-delivered IL-27 a potential immunotherapeutic for cancer?

Liu, JQ; Zhu, JM; Hu, AY; Zhang, A; Yang, CBX; Yu, JY; Ghoshal, K; Basu, S; Bai, XF

Bai, XF (corresponding author), Ohio State Univ, Coll Med, Dept Pathol, 129 Hamilton Hall,1645 Neil Ave, Columbus, OH 43210 USA.; Bai, XF (corresponding author), Ohio State Univ, Comprehens Canc Ctr, 129 Hamilton Hall,1645 Neil Ave, Columbus, OH 43210 USA.

AMERICAN JOURNAL OF CANCER RESEARCH, 2020; 10 (11): 3565

Abstract

Cytokines are one of the first immunotherapeutics utilized in trials of human cancers with significant success. However, due to their significant toxi......

Full Text Link