Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

O'Brien, LL; Combes, AN; Short, KM; Lindstrom, NO; Whitney, PH; Cullen-McEwen, LA; Ju, A; Abdelhalim, A; Michos, O; Bertram, JF; Smyth, IM; Little, MH; McMahon, AP

O'Brien, LL; McMahon, AP (reprint author), Univ Southern Calif, Keck Sch Med, Dept Stem Cell Biol & Regenerat Med, Eli & Edythe Broad CIRM Ctr Regenerat Med & Stem, Los Angeles, CA 90007 USA.

ELIFE, 2018; 7 ():

Abstract

A normal endowment of nephrons in the mammalian kidney requires a balance of nephron progenitor self-renewal and differentiation throughout developmen......

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