Synthesis of novel (E)-1-(2-(2-(4(dimethylamino) benzylidene) hydrazinyl)-4-methylthiazol-5-yl)ethanone derivatives as ecto-5 '-nucleotidase inhibitors

Hassan, S; Channar, PA; Larik, FA; Saeed, A; Shah, HS; Lecka, J; Sevigny, J; Iqbal, J

Iqbal, J (reprint author), COMSATS Univ Islamabad, Ctr Adv Drug Res, Abbottabad Campus, Abbottabad 22060, Pakistan.; Saeed, A (reprint author), Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan.

ROYAL SOCIETY OPEN SCIENCE, 2018; 5 (9):

Abstract

Ecto-5'-nucleotidase (e5'NT), a membrane-bound enzyme and an essential member of ecto-nucleotidases which regulates extracellular purinergic signallin......

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