Extrachromosomal DNA amplifications in cancer

Yi, E; Gonzalez, RC; Henssen, AG; Verhaak, RGW

Verhaak, RGW (通讯作者)，Jackson Lab Genom Med, Farmington, CT 06032 USA.;Henssen, AG (通讯作者)，Charite Univ Med Berlin, Dept Paediat Oncol Hematol, Berlin, Germany.;Henssen, AG (通讯作者)，MDC & Charite Berlin, Expt & Clin Res Ctr ECRC, Berlin, Germany.;Henssen, AG (通讯作者)，Max Delbruck Ctr Mol Med BIMSB BIH, Berlin, Germany.;Henssen, AG (通讯作者)，Berlin Inst Hlth, Berlin, Germany.;Henssen, AG (通讯作者)，German Canc Consortium DKTK, Partner Site Berlin, Heidelberg, Germany.;Henssen, AG (通讯作者)，German Canc Res Ctr, He

NATURE REVIEWS GENETICS, 2022; 23 (12): 760

Abstract

In this Review, the authors discuss our latest understanding of extrachromosomal DNA (ecDNA), a type of circular DNA element commonly found in cancers......

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