Optimization of Protein-Protein Interaction Measurements for Drug Discovery Using AFM Force Spectroscopy

Yang, YL; Zeng, BX; Sun, ZY; Esfahani, AM; Hou, J; Jiao, ND; Liu, LQ; Chen, LL; Basson, MD; Dong, LX; Yang, RG; Xi, N

Xi, N (reprint author), Michigan State Univ, Dept Elect & Comp Engn, E Lansing, MI 48823 USA.; Yang, RG (reprint author), Univ Nebraska Lincoln, Dept Mech & Mat Engn, Lincoln, NE 68588 USA.

IEEE TRANSACTIONS ON NANOTECHNOLOGY, 2019; 18 (): 509

Abstract

Increasingly targeted in drug discovery, protein-protein interactions challenge current high throughput screening technologies in the pharmaceutical i......

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