Flexible pri-miRNA structures enable tunable production of 5' isomiRs

Bofill-De Ros, X; Hong, ZY; Birkenfeld, B; Alamo-Ortiz, S; Yang, AC; Dai, LS; Gu, S

Bofill-De Ros, X; Gu, S (通讯作者)，NCI, RNA Mediated Gene Regulat Sect, RNA Biol Lab, Ctr Canc Res, Frederick, MD 21702 USA.;Bofill-De Ros, X; Gu, S (通讯作者)，RNA Mediated Gene Regulat Sect, Frederick, MD 21702 USA.

RNA BIOLOGY, 2022; 19 (1): 279

Abstract

The Drosha cleavage of a pri-miRNA defines mature microRNA sequence. Drosha cleavage at alternative positions generates 5' isoforms (isomiRs) which ha......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索