Highly Selective MIF Ketonase Inhibitor KRP-6 Diminishes M1 Macrophage Polarization and Metabolic Reprogramming

Vámos, E; Kálmán, N; Sturm, EM; Nayak, BB; Teppan, J; Vántus, VB; Kovács, D; Makszin, L; Loránd, T; Gallyas, F Jr; Radnai, B

Radnai, B (通讯作者)，Univ Pecs, Med Sch, Dept Biochem & Med Chem, 12 Sziget Str, H-7624 Pecs, Hungary.

ANTIOXIDANTS, 2023; 12 (10):

Abstract

Macrophage polarization is highly involved in autoimmunity. M1 polarized macrophages drive inflammation and undergo metabolic reprogramming, involving......

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