Carnosine dipeptidase II (CNDP2) protects cells under cysteine insufficiency by hydrolyzing glutathione-related peptides

Kobayashi, S; Homma, T; Okumura, N; Han, J; Nagaoka, K; Sato, H; Konno, H; Yamada, S; Takao, T; Fujii, J

Fujii, J (corresponding author), 2-2-2 Iidanishi, Yamagata 9909585, Japan.

FREE RADICAL BIOLOGY AND MEDICINE, 2021; 174 (): 12

Abstract

The knockout (KO) of the cystine transporter xCT causes ferroptosis, a type of iron-dependent necrotic cell death, in mouse embryonic fibroblasts, but......

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