PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer

Truong, TH; Benner, EA; Hagen, KM; Temiz, NA; Kerkvliet, CP; Wang, Y; Cortes-Sanchez, E; Yang, CH; Pengo, T; Guillen, KP; Welm, BE; Telang, S; Lange, CA; Ostrander, JH; Trousdell, MC; Camila

Lange, CA; Ostrander, JH (corresponding author), Univ Minnesota, Masonic Canc Ctr, Minneapolis, MN 55455 USA.; Lange, CA; Ostrander, JH (corresponding author), Univ Minnesota, Dept Med, Div Hematol Oncol & Transplantat, Box 736 UMHC, Minneapolis, MN 55455 USA.; Lange, CA (corresponding author), Univ Minnesota, Dept Pharmacol, 3-249 Millard Hall, Minneapolis, MN 55455 USA.

ONCOGENE, 2021; 40 (25): 4384

Abstract

Recurrence of metastatic breast cancer stemming from acquired endocrine and chemotherapy resistance remains a health burden for women with luminal (ER......

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