Wt1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium

Marques, IJ; Ernst, A; Arora, P; Vianin, A; Hetke, T; Sanz-Morejon, A; Naumann, U; Odriozola, A; Langa, X; Andres-Delgado, L; Zuber, B; Torroja, C; Osterwalder, M; Simoes, FC; Englert, C; Mercader, N

Marques, IJ; Mercader, N (通讯作者),Univ Bern, Inst Anat, Dept Dev Biol & Regenerat, CH-3012 Bern, Switzerland.;Marques, IJ; Mercader, N (通讯作者),Univ Bern, Dept BioMed Res DBMR, CH-3008 Bern, Switzerland.;Mercader, N (通讯作者),Ctr Nacl Invest Cardiovasc CNIC, Madrid 28029, Spain.

DEVELOPMENT, 2022; 149 (6):

Abstract

During development, the heart grows by addition of progenitor cells to the poles of the primordial heart tube. In the zebrafish, Wilms tumor 1 transcr......

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