Effect of a strong CYP3A4 inhibitor and inducer on the pharmacokinetics of senaparib (IMP4297) in healthy volunteers: A drug-drug interaction study

Hu, XL; Hsieh, CY; Zhang, YX; Liu, WL; Xu, SM; Cai, SX; Liu, L; Zhang, M; Shi, HY; Zhang, HX; Liu, P; Li, XM; Xu, PS

Li, XM; Xu, PS (通讯作者)，Cent South Univ, Xiangya Hosp, Phase Clin Trial Ctr 1, Xiangya Rd 87, Changsha 410008, Peoples R China.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023; 89 (6): 1767

Abstract

Aims: A phase I open-label study assessed the effect of multiple oral doses of a potent CYP3A4 inhibitor (itraconazole) and inducer (rifampicin) on th......

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