Actin cytoskeleton remodeling primes RIG-I-like receptor activation

Acharya, D; Reis, R; Volcic, M; Liu, GQ; Wang, MK; Chia, BS; Nchioua, R; Gross, R; Munch, J; Kirchhoff, F; Sparrer, KMJ; Gack, MU

Gack, MU (通讯作者),Cleveland Clin, Florida Res & Innovat Ctr, Port St Lucie, FL 34987 USA.;Gack, MU (通讯作者),Univ Chicago, Dept Microbiol, Chicago, IL 60637 USA.;Sparrer, KMJ (通讯作者),Ulm Univ, Inst Mol Virol, Med Ctr, D-89081 Ulm, Germany.

CELL, 2022; 185 (19): 3588

Abstract

The current dogma of RNA-mediated innate immunity is that sensing of immunostimulatory RNA ligands is sufficient for the activation of intracellular s......

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