Assessment of histone tail modifications and transcriptional profiling during colon cancer progression reveals a global decrease in H3K4me3 activity

Triff, K; McLean, MW; Konganti, K; Pang, JH; Callaway, E; Zhou, BY; Ivanov, I; Chapkin, RS

Chapkin, RS (reprint author), Texas A&M Univ, Dept Nutr & Food Sci, College Stn, TX 77843 USA.; Chapkin, RS (reprint author), Texas A&M Univ, Program Integrat Nutr & Complex Dis, College Stn, TX 77843 USA.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2017; 1863 (6): 1392

Abstract

During colon cancer, epigenetic alterations contribute to the dysregulation of major cellular functions and signaling pathways. Modifications in chrom......

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